Absorbable cyst brushes.

Cytobrushes are used for low-invasive sample collection and screening in multiple diseases, with a significant impact on early detection, prevention, and diagnosis. This study focuses on improving the safety of cell brushing in hard-to-reach locations by exploring brush construction from absorbable materials. We investigated the efficacy of loop brushes made of absorbable suture wires of Chirlac, Chirasorb, Monocryl, PDS II, Vicryl Rapid, Glycolon, and Catgut during their operation in conjunction with fine-needle aspiration in an artificial cyst model. PDS II brushes demonstrated the highest efficiency, while Monocryl and Catgut also provided a significant brushing effect. Efficient brushes portrayed higher flexural rigidity than their counterparts, and their efficiency was inversely proportional to their plastic deformation by the needle. Our results open avenues for safer cell biopsies in hard-to-reach locations by utilizing brushes composed of absorbable materials.

Rattractor-Instant guidance of a rat into a virtual cage using the deep brain stimulation.

We developed "Rattractor" (rat attractor), a system to apply electrical stimuli to the deep brain of a rat as it stays in a specified region or a virtual cage to demonstrate an instant electrophysiological feedback guidance for animals. Two wire electrodes were implanted in the brains of nine rats. The electrodes targeted the medial forebrain bundle (MFB), which is a part of the reward system in the deep brain. Following the recovery period, the rats were placed in a plain field where they could move freely, but wired to a stimulation circuit. An image sensor installed over the field detected the subject's position, which triggered the stimulator such that the rat remained within the virtual cage. We conducted a behavioral experiment to evaluate the sojourn ratio of rats residing in the region. Thereafter, a histological analysis of the rat brain was performed to confirm the position of the stimulation sites in the brain. Seven rats survived the surgery and the recovery period without technical failures such as connector breaks. We observed that three of them tended to stay in the virtual cage during stimulation, and this effect was maintained for two weeks. Histological analysis revealed that the electrode tips were correctly placed in the MFB region of the rats. The other four subjects showed no apparent preference for the virtual cage. In these rats, we did not find electrode tips in the MFB, or could not determine their positions. Almost half of the rats tended to remain inside the virtual cage when position-related reward stimuli were triggered in the MFB region. Notably, our system did not require previous training or sequential interventions to affect the behavioral preferences of subjects. This process is similar to the situation in which sheep are chased by a shepherd dog in the desired direction.

Acoustic activity of bats at power lines correlates with relative humidity: a potential role for corona discharges.

With the ever-increasing dependency on electric power, electrical grid networks are expanding worldwide. Bats exhibit a wide diversity of foraging and flight behaviours, and their sensitivity to anthropogenic stressors suggests this group is very likely to be affected by power lines in a myriad of ways. Yet the effects of power lines on bats remains unknown. Here we assessed the responses of insectivorous bats to very high voltage power lines (VHVPL; greater than 220 kV). We implemented a paired sampling design and monitored bats acoustically at 25 pairs, one pair consisting of one forest edge near to VHVPL matched with one control forest edge. Relative humidity mediates the effects of power lines on bats: we detected bat attraction to VHVPL at high relative humidity levels and avoidance of VHVPL by bats at low relative humidity levels. We argue that the former could be explained by insect attraction to the light emitted by VHVPL owing to corona discharges while the latter may be owing to the physical presence of pylons/cables at foraging height and/or because of electromagnetic fields. Our work highlights the response of bats to power lines at foraging habitats, providing new insight into the interactions between power lines and biodiversity.

Study on mechanical properties of corroded concrete columns strengthened with SMA wires.

Ocean crossing bridges suffer from seawater corrosion all year round and their mechanical properties will be substantially diminished. In order to enhance the mechanical properties of reinforced concrete columns corroded by seawater, SMA wire is used to restrain the reinforced concrete columns corroded by seawater to study their mechanical properties. 14 specimens were produced through the test, and the natural seawater corrosion was simulated by preparing a certain concentration of synthetic seawater. The mechanical properties of SMA strengthened specimens and unreinforced specimens are compared and analyzed, including failure mode, hysteresis curve, bearing capacity, ductility, stiffness and energy dissipation; the effects of different synthetic seawater corrosion concentrations on the mechanical properties of reinforced concrete columns are discussed. The results show that the bearing capacity and stiffness of reinforced concrete columns subjected to synthetic seawater corrosion are substantially diminished than those of uncorroded specimens, and the bearing capacity of specimens decreases more with the increase of synthetic seawater corrosion concentration; synthetic seawater corrosion has obscure effect on the ductility and energy dissipation performance of the specimens. The mechanical properties of the corroded specimens strengthened with SMA wire have been substantially enhanced, particularly the energy dissipation performance and bearing capacity have been notably enhanced, and the ductility and stiffness have also been somewhat enhanced. At the same time, based on the test, the finite element model is created according to the test specimen, while the accuracy of the model is verified, and the effects of the spacing and diameter of SMA wire, the strength of concrete and the thickness of protective layer on the mechanical properties of the specimen are analyzed.

Bioelectrocatalytic CO2 Reduction by Redox Polymer-Wired Carbon Monoxide Dehydrogenase Gas Diffusion Electrodes.

The development of electrodes for efficient CO2 reduction while forming valuable compounds is critical. The use of enzymes as catalysts provides the advantage of high catalytic activity in combination with highly selective transformations. We describe the electrical wiring of a carbon monoxide dehydrogenase II from Carboxydothermus hydrogenoformans (ChCODH II) using a cobaltocene-based low-potential redox polymer for the selective reduction of CO2 to CO over gas diffusion electrodes. High catalytic current densities of up to -5.5 mA cm-2 are achieved, exceeding the performance of previously reported bioelectrodes for CO2 reduction based on either carbon monoxide dehydrogenases or formate dehydrogenases. The proposed bioelectrode reveals considerable stability with a half-life of more than 20 h of continuous operation. Product quantification using gas chromatography confirmed the selective transformation of CO2 into CO without any parasitic co-reactions at the applied potentials.

Single Wire Capacitive Wireless Power Transfer System for Wearable Biomedical Sensors Based on Flexible Graphene Film Material.

This paper provides a special flexible graphene film based capacitive wireless power transfer (FGCPT) system for powering biomedical sensors of smart wearable devices. The graphene conductive material is flexible, transparent, highly conductive, and impermeable to most gases and liquids. Generally, the coupling structure of capacitive wireless power transfer (CPT) system is consisted of metal plates. However, it is hard to use for the biomedical sensors as the low power density and big volume. The shape of graphene conductive material could be easily built and changed according to the application requirements. In this paper, the power supply of biomedical sensing system could be accomplished by a single graphene film which is acted as the receiver of FGCPT system. The 200 mW power level is achieved with the maximum 9 V output voltage. The theory and calculation are verified by the simulated and experimental results.

Numerical study of aeolian vibration characteristics and fatigue life estimation of transmission conductors.

The 2D computational fluid dynamics (CFD) model of transmission conductor is set up to simulate the aerodynamic forces varying with time on the conductor. Taking into account the geometrical nonlinearity of conductor lines, the finite element (FE) models of single span and two-span transmission lines discretized with beam elements are established. By means of the FE models, the aeolian vibrations of the conductor lines excited by the aerodynamic forces under different wind velocities are numerically simulated. The nonlinear resonant characteristics, the amplitude-frequency relations of the conductor lines during aeolian vibration are investigated, and the influences of the span length as well as the initial tension in conductors on the aeolian vibration characteristics are analyzed. Furthermore, a 3D FE model of a conductor segment and the suspension clamp is created to study the stress distributions of the 3D model corresponding to different lines during aeolian vibrations. Finally, based on the stress analysis of the 3D model, the fatigue lives of the transmission conductors during aeolian vibration under different wind velocities are estimated. The jump phenomenon induced by the nonlinear vibration is reflected by the numerical simulation considering the geometric nonlinearity, and it is found that the energy balance principle (EBP) overestimates the vibration amplitudes because it cannot take the influences of the geometrical nonlinearity and span length into account. The obtained results may provide some instructions for the prevention design of aeolian vibration.

Human reliability analysis in de-energization of power line using HEART in the context of Z-numbers.

Investigation reveals that a high percentage of incident causes are ascribed to some forms of human error. To effectively prevent incidents from happening, Human Reliability Analysis (HRA), as a structured way to represent unintentional operator contribution to system reliability, is a critical issue. Human Error Reduction and Assessment Technique (HEART) as a famous HRA technique, provides a straightforward method to estimate probabilities of human error based on the analysis of tasks. However, it faces varying levels of uncertainty in assigning of weights to each error producing condition (EPC), denoted as assessed proportion of affect (APOA), by experts. To overcome this limitation and consider the confidence level (reliability or credibility) of the experts, the current study aimed at proposing a composite HEART methodology for human error probability (HEP) assessment, which integrates HEART and Z-numbers short for, Z-HEART. The applicability and effectiveness of the Z-HEART has been illustrated in the de-energization power line as a case study. Furthermore, a sensitivity analysis is fulfilled to investigate the validity of the proposed methodology. It can be concluded that Z-HEART is feasible for assessing human error, and despite the methodological contributions, it offers many advantages for electricity distribution companies.

Why Wire Mattered: Building U.S. Networked Infrastructures, 1845-1910.

Histories of technology, communications, or infrastructure typically draw few distinctions between the telegraph machine and its network. Yet that vast wired infrastructure not only made telegraph machines socially useful, it established a material foundation for telephone- and electrical-service networks. This article emphasizes American telegraph-network development and argues that the telegraph's needs catalyzed an electrical-wire supply industry with important continuities for later wired-network technologies. This study also shows that when telegraph networks emerged in the mid-1800s, industrial constraints meant the best wire available was still abjectly deficient for network needs. Wire vexed telegraph-line builders everywhere, but especially in the United States, where promoters favored less expensive but more vulnerable overhead lines. This article demonstrates that successfully networking the American nation involved decades of building and rebuilding, hundreds of mechanical inventions, hard-won industrial advances, and considerable individual sacrifice.

Optically transparent vertical silicon nanowire arrays for live-cell imaging.

Programmable nano-bio interfaces driven by tuneable vertically configured nanostructures have recently emerged as a powerful tool for cellular manipulations and interrogations. Such interfaces have strong potential for ground-breaking advances, particularly in cellular nanobiotechnology and mechanobiology. However, the opaque nature of many nanostructured surfaces makes non-destructive, live-cell characterization of cellular behavior on vertically aligned nanostructures challenging to observe. Here, a new nanofabrication route is proposed that enables harvesting of vertically aligned silicon (Si) nanowires and their subsequent transfer onto an optically transparent substrate, with high efficiency and without artefacts. We demonstrate the potential of this route for efficient live-cell phase contrast imaging and subsequent characterization of cells growing on vertically aligned Si nanowires. This approach provides the first opportunity to understand dynamic cellular responses to a cell-nanowire interface, and thus has the potential to inform the design of future nanoscale cellular manipulation technologies.

Exploratory narrative text analysis to characterize tasks associated with injuries among electric utility line workers: EPRI Occupational Health and Safety Database 1995-2013.

BACKGROUND: Injury prevention is an important goal for electric utility line workers who are among the top 10 U.S. occupational groups sustaining fatal injuries on the job. METHODS: Using narrative text fields, we identified 10 high-risk tasks among electric utility line workers. We performed a case-control study of task-injury associations using data from the Electric Power Research Institute Occupational Health and Safety Database (1995-2013). RESULTS: Drawn from 12,323 line worker injuries, cases were individuals with a major injury (5 or more days lost work) matched to controls, individuals with a minor injury (less than 1 day lost work), on company and year of injury. Conditional logistic regression estimated adjusted odds ratios (OR) and 95% confidence intervals (95% CI). Some tasks associated with higher odds for major injuries among line workers included: climbing up/down ladder/stairs/elevator (OR = 4.3; 95% CI = 2.6, 7.4); climbing down poles and transmission towers (OR = 5.5; 95% CI = 3.6, 8.4); entering/stepping out/approaching utility trucks, bucket, or vaults (OR = 5.8; 95% CI = 4.0, 8.4); and performing repetitive work/overtime (OR = 5.5; 95% CI = 3.2, 9.5). CONCLUSIONS: Knowledge gained can be used to focus efforts and plan efficient preventive measures that reduce injury rates, time lost from work, and costs within the electric power industry.

Optimal Operation of an Urban Microgrid Using Model Predictive Control Considering Power Quality Improvements

Abstract Microgrids have been widely applied to improve the energy quality parameters of a distribution system locally, in addition to ensuring the operation of the system in an isolated manner. The Model Predictive Control (MPC) is a great solution to guarantee the operation of the system considering forecasting models and also physical restrictions of the system, which ensure the optimal operation of the Microgrid. However, the construction of a control scheme following the objectives established in order to meet the connected and isolated operation of a Microgrid is still a challenge. This paper proposes the development of an MPC control scheme that assures optimal system operation in connected and islanded mode, improving power quality indexes, ensuring network requirements, and extending battery life cycle. The proposed control operation in the connected mode can attend to the needs of the Microgrid, reducing the impacts of peak demand and the intermittent variations in renewable generation, where a linear objective function is developed for this purpose. In the islanded mode, grid requirements are guaranteed through load shedding, considering improvements in continuity indicators. Forecasting models are implemented considering the MPC approach and a detailed network model is developed. Simulation results highlight the effectiveness of the proposed control strategy.

Optimal Dispatch and Technical and Economic Feasibility Analysis of Residential Microgrids Considering Demand Side Management

Abstract The electrical system is becoming more robust with the insertion of distributed energy resources (DERs) and the need for energy autonomy by consumers, given that the current scenario is a growth in demand for electric energy. This paper aims to apply a computational model capable of determining the optimal hourly allocation of controllable loads in residence, as well as studying the optimal dispatch of residential microgrids considering management on the demand side. In addition, this paper presents an economic feasibility analysis of residential microgrids considering distributed generation from wind and solar sources, distributed storage, electric vehicles, and residential controllable loads. Thus, it was possible to conclude that in residence, the insertion of distributed energy generation and storage elements can present a significant reduction in electric energy costs, which can be even greater if these elements are associated with optimized controllable load management.

Recent Research and Development of Microgrids in Parana

Abstract Microgrids (MGs) have increasingly attracted the attention of researchers, government officials, and electricity companies for the values and services they can add to the grid. They can operate independently as a single controllable unit in a coordinated way while connected or islanded, which make them suitable to integrate the growing amount of distributed energy resources (DERs) into the distribution network (DN). An active distribution network with high penetration of DERs could be redefined into a collection of microgrids in different layers, pooling their resources together to enhance the grid's performance in the sense of electricity as a service. However, enabling a microgrid-based power system infrastructure poses challenges concerning operation and control. In this paper, a comprehensive overview of research topics regarding microgrid operation are shown in a hierarchical or stratified manner, looking for a holistic vision of a microgrid-based distribution system. First, multi-objective optimization within one microgrid is formulated aiming to minimize costs and maximize battery life is presented. Second, the interaction among MGs, DERs and the DN was modeled using the OPF technique to represent the operation of the grid as a whole. Following, a methodology for collaborative optimization of multiple MGs operating together is presented and at last a theoretical framework for MG operation through decentralized energy markets is discussed. As a result, this paper aims to contribute to a broad vision of the distribution system based on microgrid operation in all its levels.

RF Heating Analysis of Implanted lead wires under 3.0 Tesla Magnetic Resonance Imaging System.

RF heating has severely limited the application of high-field magnetic resonance imaging (MRI) in the patients with active implantable medical devices (AIMDs). Based on the finite element methods (FEMs), we study the RF heating of a lead implanted in the human body under 3.0 T MRI. The coupled simulation of electromagnetic and heat transfer is used to analyze the relationship between several factors, such as the resonance length, the implantation position, the implantation configuration, and the thermal conductivity, and RF heating. Results show that the resonance length of the lead is half of the RF wavelength, and the temperature rise exceeds the acceptable range of human body when the resonance occurs. The electromagnetic field distribution in the phantom is not uniform, so the field density around the wire may vary with different implantation positions and configurations. Temperature rise reduces with the decrease of the field density. In addition, RF heating can be reduced by increasing the thermal conductivity.

Shields on Electric Posts Prevent Primate Deaths: A Case Study at Polonnaruwa, Sri Lanka.

When monkeys, such as the toque macaques (Macaca sinica) of Sri Lanka, seek food on the ground near human habitation, they may use electrical posts to escape aggression from conspecifics, dogs, or humans. Shields mounted on electrical posts prevented monkeys from reaching the electrical wires, thereby averting their electrocution: the frequency of electrocutions (n = 0) was significantly less (p < 0.001) in the 12 years after installation of the shields than in the 12 years before (n = 18). Electric shocks were either fatal (n = 14) or caused permanent injury (n = 4) (collectively referred to as electrocutions hereafter). The shields may find broader applications in other primate species and environments wherever monkeys are attracted by human food near electrical posts. Primates and other arboreal mammals also accessed live wires from trees; at known electrocution hotspots, short spans of exposed wires were insulated by encapsulating them in PVC water pipes. It was impossible, however, to prevent electrocutions from all electric supply infrastructures that put monkeys at risk. A wider use of insulated electric conductors in planning power distribution in habitats frequented by wild animals would be desirable in preventing electric shocks to wildlife.

Novel Evolutionary Algorithm Identifies Interactions Driving Infestation of Triatoma dimidiata, a Chagas Disease Vector.

Chagas disease is a lethal, neglected tropical disease. Unfortunately, aggressive insecticide-spraying campaigns have not been able to eliminate domestic infestation of Triatoma dimidiata, the native vector in Guatemala. To target interventions toward houses most at risk of infestation, comprehensive socioeconomic and entomologic surveys were conducted in two towns in Jutiapa, Guatemala. Given the exhaustively large search space associated with combinations of risk factors, traditional statistics are limited in their ability to discover risk factor interactions. Two recently developed statistical evolutionary algorithms, specifically designed to accommodate risk factor interactions and heterogeneity, were applied to this large combinatorial search space and used in tandem to identify sets of risk factor combinations associated with infestation. The optimal model includes 10 risk factors in what is known as a third-order disjunctive normal form (i.e., infested households have chicken coops AND deteriorated bedroom walls OR an accumulation of objects AND dirt floors AND total number of occupants ≥ 5 AND years of electricity ≥ 5 OR poor hygienic condition ratings AND adobe walls AND deteriorated walls AND dogs). Houses with dirt floors and deteriorated walls have been reported previously as risk factors and align well with factors currently targeted by Ecohealth interventions to minimize infestation. However, the tandem evolutionary algorithms also identified two new socioeconomic risk factors (i.e., households having many occupants and years of electricity ≥ 5). Identifying key risk factors may help with the development of new Ecohealth interventions and/or reduce the survey time needed to identify houses most at risk.

Electromagnetic compatibility issues in hybrid wired and wireless industrial networks.

Industrial networks are currently the only communication means designed for real-time systems used in industry. Networked control systems (NCS) are still important and commonly used type of such systems operating on shop floor. As a computerized node of NCS, a programmable logic controller (PLC) is usually used. In most cases, contemporary devices of such kind are equipped with more than one network interface of various types. Typically, only one interface is activated in NCS. Sometimes, the other is used for communication between NCS and supervisory systems. Occasionally, it is additionally involved in the data transmission in the factory IT systems. In general, however, using a single network interface is a more common solution. In this paper, the mutual utilization of more than one interface is discussed in order to back up the NCS network and to manage the node-related traffic within the scope of higher level services. The question of dependability of such a system from the electromagnetic compatibility point of view is discussed. The example is provided based on Profinet via wired and wireless connection.

Fracture status of wild cranes (Grus monacha and G. vipio) found dead or in a weak condition at Izumi Plain in Japan.

The Izumi Plain in Kagoshima Prefecture, Japan, is a major wintering ground for wild cranes. Between October 2009 and March 2016, a total of 204 Hooded Cranes Grus monacha and White-naped Cranes G. vipio were found dead or in a weak condition in the plane. Of these, 56 cranes had bone fractures. The rate of incidence of fracture was considered to be higher in White-naped than in Hooded Cranes. Tibia fractures were the most common. The leg and wing fracture numbers were almost equal. Forty six percent of the fracture cases were believed to be caused by collisions with the power line.

Current/Voltage Dual-Mode Single-Wire Simultaneous Bidirectional Interface Architecture for Sensor System.

This paper presents a simultaneous bidirectional asymmetrical serial interface architecture for sensor systems. The proposed current/voltage dual-mode signaling scheme provides system synchronous clock and continuous data transmission between sensor integrated circuit (IC) and system-on-a-chip (SoC) using a single wire, which minimizes pin requirements on packages. Two types of transceiver circuits were implemented in a 65 nm CMOS technology for the sensor IC and the SoC, and they were designed for transmission rates of 1 Mb/s and 250 Kb/s, core areas of 0.008 mm2 and 0.142 mm2, and power consumptions of 7.1 µW and 145.8 µW, respectively. The transceiver circuit for the sensor IC was also applied to a monolithic PPG sensor implemented in 180 nm CMOS, and the acquisition and transmission of PPG sensor data with the transceiver for the SoC, implemented in 65 nm, was successfully achieved.